Compile Data Set for Download or QSAR
Report error Found 35 Enz. Inhib. hit(s) with all data for entry = 50021816
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 0.920nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645125(CHEMBL5574820)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645124(CHEMBL5566523)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50639171(Pamiparib | Bgb-290 | BGB-290)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM209857(US9273052, 19 | US9566277, 19)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645133(CHEMBL5572999)
Affinity DataIC50: 1.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626789(CHEMBL5441085)
Affinity DataIC50: 3.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645121(CHEMBL5566919)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645127(CHEMBL5570455)
Affinity DataIC50: 3.20nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50611327(CHEMBL5276959)
Affinity DataIC50: 3.60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50611322(CHEMBL5274535)
Affinity DataIC50: 4.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645133(CHEMBL5572999)
Affinity DataIC50: 4.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626789(CHEMBL5441085)
Affinity DataIC50: 4.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645130(CHEMBL5566839)
Affinity DataIC50: 8.70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645131(CHEMBL5572956)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50316226(MK-4827 | (S)-2-(4-(piperidin-3-yl)phenyl)-2H-inda...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609913(CHEMBL5274451)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50626785(CHEMBL5396891)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50446130(AG-014699 | AG-14447 | Rucaparib | RUCAPARIB CAMSY...)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50609913(CHEMBL5274451)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645122(CHEMBL5571005)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645122(CHEMBL5571005)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645132(CHEMBL5570496)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645128(CHEMBL5565569)
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP3(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645129(CHEMBL5565927)
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645120(CHEMBL5564571)
Affinity DataIC50: 140nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645119(CHEMBL5575086)
Affinity DataIC50: 170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645123(CHEMBL5571183)
Affinity DataIC50: 720nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645123(CHEMBL5571183)
Affinity DataIC50: 2.28E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM27566(4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbo...)
Affinity DataIC50: 3.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 2(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645126(CHEMBL5590396)
Affinity DataIC50: 4.30E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Acharya & BM Reddy College of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50645126(CHEMBL5590396)
Affinity DataIC50: 2.20E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed