Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50021110
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637119(CHEMBL5549959)
Affinity DataIC50: 6nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637125(CHEMBL5557761)
Affinity DataIC50: 11nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637118(CHEMBL5542217)
Affinity DataIC50: 12nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM507762(US11130759, Cpd. No. 24 | US11046691, Compound 24 ...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637098(CHEMBL5557849)
Affinity DataIC50: 14nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637127(CHEMBL5561133)
Affinity DataIC50: 16nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637126(CHEMBL5558726)
Affinity DataIC50: 17nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637102(CHEMBL5560825)
Affinity DataIC50: 18nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637115(CHEMBL5559159)
Affinity DataIC50: 18nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637103(CHEMBL5559663)
Affinity DataIC50: 22nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637097(CHEMBL5565126)
Affinity DataIC50: 22nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637112(CHEMBL5560183)
Affinity DataIC50: 25nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637096(CHEMBL5568212)
Affinity DataIC50: 29nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637119(CHEMBL5549959)
Affinity DataIC50: 30nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637114(CHEMBL5532223)
Affinity DataIC50: 30nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637093(CHEMBL5566494)
Affinity DataIC50: 31nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637110(CHEMBL5563344)
Affinity DataIC50: 34nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637123(CHEMBL5558456)
Affinity DataIC50: 36nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637108(CHEMBL5560026)
Affinity DataIC50: 40nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637122(CHEMBL5517657)
Affinity DataIC50: 40nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637113(CHEMBL5563550)
Affinity DataIC50: 40nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637124(CHEMBL5560119)
Affinity DataIC50: 42nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637105(CHEMBL5561357)
Affinity DataIC50: 42nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637118(CHEMBL5542217)
Affinity DataIC50: 43nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637094(CHEMBL5557591)
Affinity DataIC50: 43nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637106(CHEMBL5556562)
Affinity DataIC50: 44nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637123(CHEMBL5558456)
Affinity DataIC50: 47nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637128(CHEMBL5523636)
Affinity DataIC50: 47nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637124(CHEMBL5560119)
Affinity DataIC50: 48nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637110(CHEMBL5563344)
Affinity DataIC50: 52nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637109(CHEMBL5532050)
Affinity DataIC50: 52nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637104(CHEMBL5523372)
Affinity DataIC50: 59nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637111(CHEMBL5555870)
Affinity DataIC50: 60nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637115(CHEMBL5559159)
Affinity DataIC50: 70nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637099(CHEMBL5561963)
Affinity DataIC50: 70nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637125(CHEMBL5557761)
Affinity DataIC50: 74nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637121(CHEMBL5558467)
Affinity DataIC50: 78nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637100(CHEMBL5561779)
Affinity DataIC50: 87nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637107(CHEMBL5560624)
Affinity DataIC50: 89nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637117(CHEMBL5566122)
Affinity DataIC50: 90nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637120(CHEMBL5556830)
Affinity DataIC50: 118nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637095(CHEMBL5561633)
Affinity DataIC50: 124nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM507762(US11130759, Cpd. No. 24 | US11046691, Compound 24 ...)
Affinity DataIC50: 171nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637101(CHEMBL5555094)
Affinity DataIC50: 183nMAssay Description:Inhibition of MAT2A (unknown origin) assessed as release of inorganic phosphate using ATP/L-methionine incubated for 30 mins by colorimetric phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637126(CHEMBL5558726)
Affinity DataIC50: 184nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637113(CHEMBL5563550)
Affinity DataIC50: 254nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637127(CHEMBL5561133)
Affinity DataIC50: 285nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637102(CHEMBL5560825)
Affinity DataIC50: 321nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637114(CHEMBL5532223)
Affinity DataIC50: 342nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetS-adenosylmethionine synthase isoform type-2(Human)
Suzhou Genhouse Bio

Curated by ChEMBL
LigandPNGBDBM50637128(CHEMBL5523636)
Affinity DataIC50: 400nMAssay Description:Inhibition of MAT2A in MTAP-knock out human HCT-116 cells assessed as reduction in PRMT5-mediated symmetrical demethylation of arginine (SDMA) measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
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