Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50022028
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647357(CHEMBL5598203)
Affinity DataKd:  30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataKd:  1.32E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataKd:  4.80nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50601383(CHEMBL5177286)
Affinity DataKd:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647356(CHEMBL5597730)
Affinity DataKd:  2.20E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataKd:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647355(CHEMBL5597129)
Affinity DataKd:  5.80E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621554(CHEMBL5405105)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621556(CHEMBL5396973)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621556(CHEMBL5396973)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621554(CHEMBL5405105)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647357(CHEMBL5598203)
Affinity DataIC50: 7.40nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621552(CHEMBL5402970)
Affinity DataIC50: 7.90nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621552(CHEMBL5402970)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621575(CHEMBL5081947)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621567(CHEMBL5081437)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621575(CHEMBL5081947)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621567(CHEMBL5081437)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621554(CHEMBL5405105)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50060768(9,10-anthracenedicarboxaldehyde Bis[(4,5-dihydro-1...)
Affinity DataIC50: 140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611058(CHEMBL5279050)
Affinity DataIC50: 280nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM589244(US11555009, Compound 32)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50009672(AdoHcy | S-[1-(adenin-9-yl)-1,5-dideoxy-beta-D-rib...)
Affinity DataIC50: 520nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647347(CHEMBL1253979)
Affinity DataIC50: 640nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methylquin...)
Affinity DataIC50: 710nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647348(CHEMBL5597797)
Affinity DataIC50: 780nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50557836(CHEMBL4752151)
Affinity DataIC50: 840nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621575(CHEMBL5081947)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621567(CHEMBL5081437)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50378739(SINEFUNGIN | jm2c00120, Sinefungin)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647346(CHEMBL5597856)
Affinity DataIC50: 1.43E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM32018(cid_26248 | SMR000058958 | MLS000028577 | 4,5-diac...)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611053(CHEMBL5281651)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647354(CHEMBL5597347)
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 1.52E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetYTH domain-containing protein 1(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50129950(EBSELEN)
Affinity DataIC50: 1.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetRNA demethylase ALKBH5(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50557837(CHEMBL4753950)
Affinity DataIC50: 1.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM624850(US20230322715, Compound FTO-2)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM589237(US11555009, Compound 25)
Affinity DataIC50: 2.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 2.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50193145(Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...)
Affinity DataIC50: 2.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetN(6)-adenosine-methyltransferase catalytic subunit METTL3(Mus musculus)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50611061(CHEMBL5291234)
Affinity DataIC50: 2.81E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetN6-adenosine-methyltransferase catalytic subunit(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50621559(CHEMBL5426510)
Affinity DataIC50: 2.81E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 3.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50647349(CHEMBL5597712)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
University of Connecticut

Curated by ChEMBL
LigandPNGBDBM50108879((2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-d...)
Affinity DataIC50: 3.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
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