Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50021067
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665809(US20240116922, Example 111 | N-(1-cyclopropyl-2-ox...)
Affinity DataIC50: 0.160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636469(CHEMBL5549771)
Affinity DataIC50: 0.170nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665787(US20240116922, Example 89 | 2-(2-oxabicyclo[2.1.1]...)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636471(CHEMBL5532502)
Affinity DataIC50: 0.190nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665861(US20240116922, Example 163 | N-(1-((1R,2S)-2-fluor...)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665830(US20240116922, Example 132)
Affinity DataIC50: 0.220nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665875(US20240116922, Example 177)
Affinity DataIC50: 0.220nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 0.230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636473(CHEMBL5565718)
Affinity DataIC50: 0.260nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636474(CHEMBL5556725)
Affinity DataIC50: 0.290nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636468(CHEMBL5556169)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665710(US20240116922, Example 12 | N-(1-cyclopropyl-2-oxo...)
Affinity DataIC50: 0.340nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636463(CHEMBL5560519)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665752(US20240116922, Example 54)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665895(US20240116922, Comparator 2B)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665834(US20240116922, Example 136)
Affinity DataIC50: 0.560nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636467(CHEMBL5560188)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665708(US20240116922, Example 10)
Affinity DataIC50: 0.780nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636472(CHEMBL5557994)
Affinity DataIC50: 1.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665906(US20240116922, Comparator 2D)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636470(CHEMBL5527875)
Affinity DataIC50: 2.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636464(CHEMBL5556544)
Affinity DataIC50: 4.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636466(CHEMBL5563693)
Affinity DataIC50: 8.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM50636465(CHEMBL5560848)
Affinity DataIC50: 8.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 418nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 752nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetBDNF/NT-3 growth factors receptor(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 1.16E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 2.17E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetRho-associated protein kinase 1(Human)
Biogen Inc.

Curated by ChEMBL
LigandPNGBDBM665716(US20240116922, Example 18)
Affinity DataIC50: 2.75E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed