Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 50021710
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataEC50:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50643875(CHEMBL5579682)
Affinity DataEC50:  6.10E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50643874(CHEMBL5574976)
Affinity DataEC50:  1.40E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658061(US20240083897, Compound 14 | 6-[3-(5-chloro-2-meth...)
Affinity DataEC50:  140nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658055(US20240083897, Compound 8 | 6-[3-(5-cyano-2-methox...)
Affinity DataEC50:  750nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658053(US20240083897, Compound 6 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50:  460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50:  440nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658051(US20240083897, Compound 4 | 2-[3-(5-Chloro-2-metho...)
Affinity DataEC50:  110nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataEC50:  72nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658118(US20240083897, Compound 67-1)
Affinity DataEC50:  120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658074(US20240083897, Compound 27-1)
Affinity DataEC50:  240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658048(US20240083897, Compound 1 | 6-[3-(5-chloro-2-metho...)
Affinity DataEC50:  160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643875(CHEMBL5579682)
Affinity DataEC50:  160nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643874(CHEMBL5574976)
Affinity DataEC50:  46nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658048(US20240083897, Compound 1 | 6-[3-(5-chloro-2-metho...)
Affinity DataEC50:  4.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658074(US20240083897, Compound 27-1)
Affinity DataEC50:  460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658118(US20240083897, Compound 67-1)
Affinity DataEC50:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataEC50:  6.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658051(US20240083897, Compound 4 | 2-[3-(5-Chloro-2-metho...)
Affinity DataEC50:  870nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658053(US20240083897, Compound 6 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50:  5.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658055(US20240083897, Compound 8 | 6-[3-(5-cyano-2-methox...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658061(US20240083897, Compound 14 | 6-[3-(5-chloro-2-meth...)
Affinity DataEC50:  1.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643874(CHEMBL5574976)
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658048(US20240083897, Compound 1 | 6-[3-(5-chloro-2-metho...)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658051(US20240083897, Compound 4 | 2-[3-(5-Chloro-2-metho...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643875(CHEMBL5579682)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658061(US20240083897, Compound 14 | 6-[3-(5-chloro-2-meth...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658053(US20240083897, Compound 6 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658118(US20240083897, Compound 67-1)
Affinity DataIC50: 39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 47nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658055(US20240083897, Compound 8 | 6-[3-(5-cyano-2-methox...)
Affinity DataIC50: 63nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658074(US20240083897, Compound 27-1)
Affinity DataIC50: 69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 77nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643876(CHEMBL5590134)
Affinity DataIC50: 250nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658063(US20240083897, Compound 16 | 3-[3-(5-Chloro-2-meth...)
Affinity DataIC50: 400nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643877(CHEMBL5590151)
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 2.60E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 2.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 3.40E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM50643878(CHEMBL5570666)
Affinity DataIC50: 3.70E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 5.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 9.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase Nek1(Human)
Pharmaron UK Ltd.

Curated by ChEMBL
LigandPNGBDBM658050(US20240083897, Compound 3)
Affinity DataIC50: 9.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed