Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50019630
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621185(CHEMBL5417330)
Affinity DataEC50:  43nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataEC50:  3nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621184(CHEMBL5439877)
Affinity DataEC50:  33nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50247997(Alvesco | Alvesco 160 | Alvesco 80 | Ciclesonide |...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621183(CHEMBL5435559)
Affinity DataEC50:  84nMAssay Description:Agonist activity at glucocorticoid receptor (unknown origin) expressed in K562 cellsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50247997(Alvesco | Alvesco 160 | Alvesco 80 | Ciclesonide |...)
Affinity DataIC50: 2nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM86696(desisobutyryl-ciclesonide | des-CIC)
Affinity DataIC50: 2nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50: 3nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621185(CHEMBL5417330)
Affinity DataIC50: 5nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50: 20nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621184(CHEMBL5439877)
Affinity DataIC50: 34nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621183(CHEMBL5435559)
Affinity DataIC50: 53nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621187(CHEMBL5413057)
Affinity DataIC50: 63nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetGlucocorticoid receptor(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM50621186(CHEMBL5396710)
Affinity DataIC50: 911nMAssay Description:Inhibition of glucocorticoid receptor (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50: 1.84E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 1A2(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Abbvi

Curated by ChEMBL
LigandPNGBDBM445033(US10668167, Compound 41)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed