Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019779
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593227(CHEMBL5177023)
Affinity DataIC50: 2nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593226(CHEMBL5184760)
Affinity DataIC50: 3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593222(CHEMBL5208056)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593225(CHEMBL5193772)
Affinity DataIC50: 6nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593223(CHEMBL5193594)
Affinity DataIC50: 7nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Smith, Gambrell & Russell

Curated by ChEMBL
LigandPNGBDBM50593224(CHEMBL5170519)
Affinity DataIC50: 10nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant (unknown origin) phosphorylation expressed in mouse BaF3 cells incubated for 4 hrs by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed