Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50020598
TargetSerine/threonine-protein kinase mTOR(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631719(CHEMBL5437417)
Affinity DataIC50: 103nMAssay Description:Inhibition of mTOR in human SR cells by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631719(CHEMBL5437417)
Affinity DataIC50: 130nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631719(CHEMBL5437417)
Affinity DataIC50: 170nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50088378(CHEBI:68478 | Afinitor | Afinitor Disperz | Everol...)
Affinity DataIC50: 530nMAssay Description:Inhibition of mTOR (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631719(CHEMBL5437417)
Affinity DataIC50: 760nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631719(CHEMBL5437417)
Affinity DataIC50: 830nMAssay Description:Inhibition of mTOR (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631720(CHEMBL5432408)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631720(CHEMBL5432408)
Affinity DataIC50: 1.98E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631720(CHEMBL5432408)
Affinity DataIC50: 2.85E+3nMAssay Description:Inhibition of mTOR (unknown origin) incubated for 1 hr by ELISA analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM50631720(CHEMBL5432408)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 3.48E+3nMAssay Description:Inhibition of PI3Kdelta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 5.43E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Health Affairs Directorate - Giza

Curated by ChEMBL
LigandPNGBDBM12915(CHEMBL98350 | 2-(morpholin-4-yl)-8-phenyl-4H-chrom...)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2024
Entry Details
PubMed