Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50021623
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642779(CHEMBL5573642)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251508(US9452998, 57)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251528(US9452998, 77)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251522(US9452998, 71)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251513(US9452998, 62)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251529(US9452998, 78)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642785(CHEMBL5592487)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251522(US9452998, 71)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251504(US9452998, 53)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251494(US9452998, 43)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251529(US9452998, 78)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251528(US9452998, 77)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251500(US9452998, 49)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251532(US9452998, 81)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642780(CHEMBL5566264)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251513(US9452998, 62)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642779(CHEMBL5573642)
Affinity DataIC50: 0.600nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251482(US9452998, 31)
Affinity DataIC50: 0.840nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251508(US9452998, 57)
Affinity DataIC50: 0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251504(US9452998, 53)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642780(CHEMBL5566264)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251500(US9452998, 49)
Affinity DataIC50: 1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251494(US9452998, 43)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251453(US9452998, 2)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642785(CHEMBL5592487)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251577(US9452998, 1)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 2.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C epsilon type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
Affinity DataIC50: 2.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642783(CHEMBL5564760)
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251453(US9452998, 2)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251577(US9452998, 1)
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C epsilon type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C eta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C delta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C delta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251482(US9452998, 31)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C beta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 7.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642783(CHEMBL5564760)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642782(CHEMBL5565713)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50642782(CHEMBL5565713)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C eta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C beta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM33971(Sotrastaurin | AEB071 | med.21724, Compound 190)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C theta type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251532(US9452998, 81)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetProtein kinase C alpha type(Human)
Novartis Institutes for Biomedical Research

Curated by ChEMBL
LigandPNGBDBM251460(US9452998, 9)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
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