Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50020884
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634512(CHEMBL5409100)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634511(CHEMBL5436764)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634521(CHEMBL5429626)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634517(CHEMBL5397047)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634520(CHEMBL5413414)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634518(CHEMBL5395695)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634516(CHEMBL5437060)
Affinity DataIC50: 240nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634514(CHEMBL5398846)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634519(CHEMBL5417628)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634515(CHEMBL5400823)
Affinity DataIC50: 970nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634512(CHEMBL5409100)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634521(CHEMBL5429626)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634518(CHEMBL5395695)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634511(CHEMBL5436764)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634513(CHEMBL5420068)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634514(CHEMBL5398846)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634515(CHEMBL5400823)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634516(CHEMBL5437060)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634517(CHEMBL5397047)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634519(CHEMBL5417628)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 4A(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634520(CHEMBL5413414)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM4A assessed as decarboxylation of [1-14C] alphaKG at pH 7.4 using H3K9me3 as substrates incubated for 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetLysine-specific demethylase 5B(Human)
Arrival Discovery

Curated by ChEMBL
LigandPNGBDBM50634513(CHEMBL5420068)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human recombinant KDM5B assessed as decarboxylation of [1-14C] alphaKG by measuring 14CO2 release using H3K4me3 as substrate incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed