Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50019477
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 167nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 239nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 251nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 599nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619528(CHEMBL5400930)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619527(CHEMBL5420997)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50619526(CHEMBL5429263)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Daiichi Sankyo Co.

Curated by ChEMBL
LigandPNGBDBM50048525(CHEMBL2426254)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of N-terminal His6-tagged human EGFR L858R/T790M/C797S mutant expressed in Sf9 cells assessed as decrease in substrate phosphorylation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)