Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50020993
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM557274(US11352354, Example V-c-39)
Affinity DataKd: >3.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM557265(US11352354, Example V-c-17)
Affinity DataKd:  6.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635837(CHEMBL5555919)
Affinity DataKd:  0.910nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50595937(CHEMBL5194705)
Affinity DataKd:  32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50021656(LY-3009104 | INCB-028050 | BARICITINIB | US1011290...)
Affinity DataKd:  8.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50311470(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
Affinity DataKd:  1.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM4814(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Affinity DataKd:  11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetAP2-associated protein kinase 1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50273541(N-(5-(4-cyanophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl...)
Affinity DataKd:  0.120nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601761(CHEMBL5203869 | US11773078, Example 263)
Affinity DataIC50: 0.160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601747(CHEMBL5175553 | US11773078, Example 11)
Affinity DataIC50: 0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601762(CHEMBL5190891 | US11773078, Example 369)
Affinity DataIC50: 0.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuropilin-1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635832(CHEMBL5557974)
Affinity DataIC50: 0.598nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50592586(CHEMBL4852855 | US11753373, Compound C-2-b)
Affinity DataIC50: 1.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM621498(US11773078, Example 250)
Affinity DataIC50: 1.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635839(CHEMBL5557909)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50601754(CHEMBL5208861 | US11773078, Example 207)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50429615(CHEMBL2334586)
Affinity DataIC50: 2.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50424712(Camostat Mesilate | Foipan | CAMOSTAT)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635836(CHEMBL2032358)
Affinity DataIC50: 5.10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590929(CHEMBL4303292 | US20240016810, Compound TABLE 16.2...)
Affinity DataIC50: 5.20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590931(CHEMBL5181163)
Affinity DataIC50: 6.10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635840(CHEMBL5523484)
Affinity DataIC50: 6.90nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635838(CHEMBL5568317)
Affinity DataIC50: 9.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 12nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM621376(US11773078, Example 128)
Affinity DataIC50: 13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590927(Apilimod | Sta-5326 | STA 5326 | STA-5326 | APILIM...)
Affinity DataIC50: 14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590928(CHEMBL2178735)
Affinity DataIC50: 33nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50084655([(S)-1-((S)-1-Formyl-pentylcarbamoyl)-3-methyl-but...)
Affinity DataIC50: 44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590930(CHEMBL5202422)
Affinity DataIC50: 61nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635841(CHEMBL1185793)
Affinity DataIC50: 70nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50592586(CHEMBL4852855 | US11753373, Compound C-2-b)
Affinity DataIC50: 105nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50104435(4-(6-Guanidino-hexanoyloxy)-benzoic acid ethyl est...)
Affinity DataIC50: 130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
Target1-phosphatidylinositol 3-phosphate 5-kinase(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50590948(CHEMBL5194568)
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50114539(Otamixaban | (2R,3R)-2-(3-Carbamimidoyl-benzyl)-3-...)
Affinity DataIC50: 620nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetTransmembrane protease serine 2(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50084952(4'-Carbamimidoyl-2'-methyl-biphenyl-4-carboxylic a...)
Affinity DataIC50: 1.24E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635833(TEICOPLANIN AGLYCON)
Affinity DataIC50: 1.46E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 3.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 5.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635835(CHEMBL4744444)
Affinity DataIC50: 7.87E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 8.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50084655([(S)-1-((S)-1-Formyl-pentylcarbamoyl)-3-methyl-but...)
Affinity DataIC50: 1.04E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetNeuropilin-1(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50538774(CHEMBL3322197)
Affinity DataIC50: 3.40E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635834(CHEMBL5550069)
Affinity DataIC50: 1.27E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetProcathepsin L(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50635833(TEICOPLANIN AGLYCON)
Affinity DataIC50: 2.08E+5nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50552672(CHEMBL4790628)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50588186(CHEMBL403278 | SN-20440)
Affinity DataKi:  3.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50333188(2,2'-(1,1'-(5-amino-1,3-phenylene)bis(ethan-1-yl-1...)
Affinity DataKi:  3.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50197751((2E)-2-{2-[(4-chlorobenzyl)oxy]benzylidene}hydrazi...)
Affinity DataKi:  1.18E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetFurin(Human)
National Clinical Research Center for Geriatrics

Curated by ChEMBL
LigandPNGBDBM50333198(2-(1-phenylethylidene)hydrazinecarboximidamide | C...)
Affinity DataKi:  2.73E+5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed