Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50020521
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nanjing Normal University

Curated by ChEMBL
LigandPNGBDBM50630815(CHEMBL5397454)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human FTO assessed as reduction in enzyme-mediated demethylation of m6A-ssDNA incubated for 2 hrs by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nanjing Normal University

Curated by ChEMBL
LigandPNGBDBM50630814(CHEMBL444311)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of human FTO assessed as reduction in enzyme-mediated demethylation of m6A-ssDNA incubated for 2 hrs by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nanjing Normal University

Curated by ChEMBL
LigandPNGBDBM50033894(NCI-308847 | 5-Amino-2-(2-dimethylamino-ethyl)-ben...)
Affinity DataIC50: 1.88E+4nMAssay Description:Inhibition of human FTO assessed as reduction in enzyme-mediated demethylation of m6A-ssDNA incubated for 2 hrs by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Nanjing Normal University

Curated by ChEMBL
LigandPNGBDBM50630813(Mitonafide | Mitonafida | NSC-300288 | MITONAFIDE)
Affinity DataIC50: 3.48E+4nMAssay Description:Inhibition of human FTO assessed as reduction in enzyme-mediated demethylation of m6A-ssDNA incubated for 2 hrs by PAGE analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2024
Entry Details
PubMed