Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50020869
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50634379(CHEMBL5423615)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PTP1B (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50634379(CHEMBL5423615)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of PTPN2 (unknown origin) using pNPP as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50634380(CHEMBL5415903)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PTP1B (unknown origin) using DiFMUP as substrate by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50634380(CHEMBL5415903)
Affinity DataIC50: 11nMAssay Description:Inhibition of PTPN2 (unknown origin) using DiFMUP as substrate by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50612105(CHEMBL5268430)
Affinity DataIC50: 104nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50099692(N-(9,10-Dioxo-9,10-dihydro-phenanthrene-2-yl)-2,2-...)
Affinity DataIC50: 950nMAssay Description:Inhibition of 6xHis-tagged PTP1B (unknown origin) Escherichia coli BL21 (DE3)-RIL using OMFP as substrate incubated for 30 mins by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50131550((S)-4-((S)-1-amino-3-(4-(difluoro(phosphono)methyl...)
Affinity DataKi:  26nMAssay Description:Binding affinity to human PTPN2 (1 to 288 residues) using pNPP as substrate assessed as inhibition constant by absorbance based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed