Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019455
TargetEpidermal growth factor receptor(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50619386(CHEMBL5424516)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50029668(AZD-9291 | Osimertinib | US10085983, Compound AZD-...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant in human NCI-H1975 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Mouse)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50468244(CHEMBL4284413)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of wild type EGFR in mouse BaF3 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50468244(CHEMBL4284413)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant in human NCI-H1975 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50619386(CHEMBL5424516)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of EGFR L858R/T790M/C797S triple mutant in human NCI-H1975 cells assessed as cell growth inhibition measured after 72 hrs by CellTiter-Glo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed