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Found
13
Enz. Inhib. hit(s) with all data for entry = 50021123
Target
Vascular endothelial growth factor receptor 2
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50637221
(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
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Copy InChI
Affinity Data
IC50: 0.350nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Proto-oncogene tyrosine-protein kinase receptor Ret
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Epidermal growth factor receptor
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50311470
(CHEMBL1079742 | Erlotinib | CP-358774-01 | OSI-774...)
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Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
PDB
3D Structure (crystal)
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Target
Platelet-derived growth factor receptor beta
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM4814
(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
RAF proto-oncogene serine/threonine-protein kinase
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 2.5nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
UniProtKB/TrEMBL
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 2
(Mouse)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 4.20nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Mast/stem cell growth factor receptor Kit
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 7nM
More data for this Ligand-Target Pair
Target Info
PDB
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 1
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 13nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Platelet-derived growth factor receptor beta
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 22nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 1
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50637221
(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 33nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 3
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50637221
(Fruquintinib | Hmpl-013 | HMPL-013 | HMPL013 | Fru...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 35nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 3
(Mouse)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM50363397
(CHEMBL1946170 | REGORAFENIB | US10183928, Regorafe...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 46nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL
Target
Vascular endothelial growth factor receptor 2
(Human)
KU Leuven
Curated by
ChEMBL
Ligand
BDBM4814
(SUNITINIB MALATE | CHEMBL535 | N-[2-(diethylamino)...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 80nM
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
ChEBI
CHEMBL
DrugBank
PC cid
PC sid
Similars
In Depth
Date in BDB:
10/11/2025
Entry Details
Copy Entry DOI
PubMed
Copy Rxn URL