Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50022452
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM14774(DAXAS | 3-(cyclopropylmethoxy)-N-(3,5-dichloropyri...)
Affinity DataIC50: 0.390nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50238854(CHEBI:58987 | Revatio | Sildenafil Citrate | UK-92...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50248919((S)-N-(2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsu...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 90nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetCone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha'(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652433(Ethaverine hydrochloride | Ethaverine hcl | Ethylp...)
Affinity DataIC50: 410nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 420nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50639239(Rolipram | (r,s)-rolipram | NSC-760125 | SB-95952 ...)
Affinity DataIC50: 460nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652434(CHEMBL5646602)
Affinity DataIC50: 940nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50335638(5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.29E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)
Affinity DataIC50: 1.74E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 1.77E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.78E+3nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 2.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 2.25E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM28031(N-{4-[(2-amino-3-chloropyridin-4-yl)oxy]-3-fluorop...)
Affinity DataIC50: 2.46E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetDual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652432(CHEMBL5639763)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50113739(2-{(2-Hydroxy-ethyl)-[9-isopropyl-6-(4-methoxy-ben...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50652431(CHEMBL5647232)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPDB
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed