Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50020859
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634267(CHEMBL5402445)
Affinity DataIC50: 18nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634266(CHEMBL5433814)
Affinity DataIC50: 22nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634272(CHEMBL5422088)
Affinity DataIC50: 35nMAssay Description:Inhibition of URAT1 (unknown origin) stably expressed in HEK293 cells assessed as reduction of uric acid uptake measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634269(CHEMBL4089920)
Affinity DataIC50: 50nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation by double beam spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50518676(CHEMBL4453888)
Affinity DataIC50: 94nMAssay Description:Inhibition of URAT1 (unknown origin) stably expressed in HEK293 cells assessed as reduction of uric acid uptake measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetSolute carrier family 22 member 12(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634273(CHEMBL5433470)
Affinity DataIC50: 230nMAssay Description:Inhibition of URAT1 (unknown origin) stably expressed in HEK293 cells assessed as reduction of uric acid uptake measured after 48 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 400nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23414(5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-chr...)
Affinity DataIC50: 530nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation by FluoSTAR OPTIMA plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50633039(CHEMBL5412360)
Affinity DataIC50: 590nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50121025(broussochalcone A | (E)-1-[2,4-Dihydroxy-5-(3-meth...)
Affinity DataIC50: 600nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate incubated for 5 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634268(CHEMBL5407581)
Affinity DataIC50: 620nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation preincubated for 10 mins followed by subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM23418((2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3...)
Affinity DataIC50: 840nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation by FluoSTAR OPTIMA plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM7461(5,7-dihydroxy-2-phenyl-4H-chromen-4-one | cid_5281...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate preincubated for 3 hrs followed by substrate addition by UV-Vis spectrophotometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 1.73E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50267789(CHEMBL2235107)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate incubated for 5 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate incubated for 5 minMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634271(CHEMBL5411013)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of Bovine milk xanthine oxidase using xanthine as substrate assessed as decrease in uric acid level preincubated for 5 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 2.93E+3nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate preincubated for 3 hrs followed by substrate addition by UV-Vis spectrophotometric anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50634270(CHEMBL5405319)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of XO (unknown origin) by microtitre plate analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 3.53E+3nMAssay Description:Inhibition of XO (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Bovine)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 8.79E+3nMAssay Description:Inhibition of Bovine milk xanthine oxidase using xanthine as substrate assessed as decrease in uric acid level preincubated for 5 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140241(CHEBI:40279 | Allopurinol | Aloral | Aluline 100 |...)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of XO (unknown origin) using xanthine as substrate assessed as reduction in uric acid formation by FluoSTAR OPTIMA plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetXanthine dehydrogenase/oxidase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM34571(6,7-dihydroxychromen-2-one | 6,7-dihydroxy-1-benzo...)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of XO (unknown origin) by microtitre plate analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed