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Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50020858
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634259(CHEMBL5435075)
Affinity DataKi:  6.80nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  7.30nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634255(CHEMBL5436128)
Affinity DataKi:  10nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  12nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634255(CHEMBL5436128)
Affinity DataKi:  12nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  17nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634256(CHEMBL5411012)
Affinity DataKi:  21nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634259(CHEMBL5435075)
Affinity DataKi:  24nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  25nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50133408(CHEMBL3632844)
Affinity DataKi:  25nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634260(CHEMBL5434757)
Affinity DataKi:  29nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634262(CHEMBL5427397)
Affinity DataKi:  32nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634259(CHEMBL5435075)
Affinity DataKi:  34nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634256(CHEMBL5411012)
Affinity DataKi:  35nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634258(CHEMBL5417966)
Affinity DataKi:  39nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634260(CHEMBL5434757)
Affinity DataKi:  39nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634262(CHEMBL5427397)
Affinity DataKi:  42nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634255(CHEMBL5436128)
Affinity DataKi:  45nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634254(CHEMBL5416640)
Affinity DataKi:  47nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634262(CHEMBL5427397)
Affinity DataKi:  52nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634264(CHEMBL5413719)
Affinity DataKi:  58nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634254(CHEMBL5416640)
Affinity DataKi:  58nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634258(CHEMBL5417966)
Affinity DataKi:  59nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50133408(CHEMBL3632844)
Affinity DataKi:  62nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634254(CHEMBL5416640)
Affinity DataKi:  66nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  68nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634264(CHEMBL5413719)
Affinity DataKi:  69nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634258(CHEMBL5417966)
Affinity DataKi:  72nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634254(CHEMBL5416640)
Affinity DataKi:  73nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634256(CHEMBL5411012)
Affinity DataKi:  84nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50133408(CHEMBL3632844)
Affinity DataKi:  86nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50133408(CHEMBL3632844)
Affinity DataKi:  92nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634255(CHEMBL5436128)
Affinity DataKi:  96nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634260(CHEMBL5434757)
Affinity DataKi:  187nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634258(CHEMBL5417966)
Affinity DataKi:  209nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634264(CHEMBL5413719)
Affinity DataKi:  229nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634257(CHEMBL5427767)
Affinity DataKi:  229nMAssay Description:Binding affinity to human recombinant CA9 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM10880(Acetazolamide, AAZ | AZA2 | CHEMBL20 | Acetazolami...)
Affinity DataKi:  250nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634259(CHEMBL5435075)
Affinity DataKi:  272nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634262(CHEMBL5427397)
Affinity DataKi:  328nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634257(CHEMBL5427767)
Affinity DataKi:  425nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634263(CHEMBL5412673)
Affinity DataKi:  446nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634256(CHEMBL5411012)
Affinity DataKi:  644nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 2(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634257(CHEMBL5427767)
Affinity DataKi:  888nMAssay Description:Binding affinity to human recombinant CA2 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634264(CHEMBL5413719)
Affinity DataKi:  943nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634261(CHEMBL5423264)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634260(CHEMBL5434757)
Affinity DataKi:  1.03E+3nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634265(CHEMBL5398809)
Affinity DataKi:  1.19E+3nMAssay Description:Binding affinity to human recombinant CA12 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Catholic University of The Sacred Heart

Curated by ChEMBL
LigandPNGBDBM50634257(CHEMBL5427767)
Affinity DataKi:  5.84E+3nMAssay Description:Binding affinity to human recombinant CA1 assessed as inhibition constant incubated for 15 mins by phenol red dye based stopped flow CO2 hydration as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
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