Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50020368
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 18nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629325(CHEMBL5423012)
Affinity DataIC50: 30nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629319(CHEMBL5415136)
Affinity DataIC50: 35nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629328(CHEMBL5430657)
Affinity DataIC50: 48nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629324(CHEMBL5397714)
Affinity DataIC50: 53nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629321(CHEMBL5424940)
Affinity DataIC50: 53nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629314(CHEMBL5435971)
Affinity DataIC50: 65nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629330(CHEMBL5396396)
Affinity DataIC50: 73nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629320(CHEMBL5431659)
Affinity DataIC50: 74nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629322(CHEMBL5421651)
Affinity DataIC50: 92nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629326(CHEMBL5417082)
Affinity DataIC50: 112nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM38019(US10093646, Compound 1 | US10301278, Example 00003...)
Affinity DataIC50: 122nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629311(CHEMBL5416270)
Affinity DataIC50: 137nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629313(CHEMBL5433260)
Affinity DataIC50: 142nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629333(CHEMBL5396867)
Affinity DataIC50: 159nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629312(CHEMBL5408024)
Affinity DataIC50: 184nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629317(CHEMBL5424837)
Affinity DataIC50: 210nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629329(CHEMBL5402661)
Affinity DataIC50: 252nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629316(CHEMBL5400948)
Affinity DataIC50: 396nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629306(CHEMBL5422106)
Affinity DataIC50: 414nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629315(CHEMBL5410896)
Affinity DataIC50: 715nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629308(CHEMBL5434296)
Affinity DataIC50: 1.15E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629331(CHEMBL5405120)
Affinity DataIC50: 2.00E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629323(CHEMBL5431213)
Affinity DataIC50: 3.21E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629309(CHEMBL5425459)
Affinity DataIC50: 3.40E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629332(CHEMBL5426966)
Affinity DataIC50: 3.76E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629318(CHEMBL5416146)
Affinity DataIC50: 4.85E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629305(CHEMBL5401484)
Affinity DataIC50: 6.26E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629307(CHEMBL5416635)
Affinity DataIC50: 6.36E+3nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629310(CHEMBL5404487)
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric Inhibition of H2N-LN(pY)IDLDLV(dPEG8)LST(pY)ASINFQKASINFQK-amide-activated SHP2 (unknown origin) using DiFMUP as substrate pretreated with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 11(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SHP2 PTP domain (unknown origin) using DiFMUP as substrate pretreated with enzyme for 20 mins followed by substrate addition and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50629327(CHEMBL5428525)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SHP1 (unknown origin) using DiFMUP as substrate pretreated with enzyme for 20 mins followed by substrate addition and measured for 2 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed