Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50020012
TargetSerine/threonine-protein kinase haspin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50625571(CHEMBL5440655)
Affinity DataKd:  0.550nMAssay Description:Inhibition of haspin (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50587785(CHEMBL5178368)
Affinity DataKd: <0.170nMAssay Description:Inhibition of haspin (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50625571(CHEMBL5440655)
Affinity DataIC50: 0.0240nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50625571(CHEMBL5440655)
Affinity DataIC50: 0.121nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 0.187nMAssay Description:Inhibition of FLT3 D835Y mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM144315(US8969336, 577 | US8969336, 547 | Gilteritinib | U...)
Affinity DataIC50: 0.199nMAssay Description:Inhibition of FLT3 ITD mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase haspin(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50466167(CHEMBL4278808)
Affinity DataIC50: 14nMAssay Description:Inhibition of haspin (unknown origin) incubated for 3 hrs by ADP-GloTM kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed