Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50021500
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.0190nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.0240nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.0600nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM36609(Rapamycin C-7, analog 4 | SIROLIMUS | US11603377, ...)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50145416(GSK2126458 | Omipalisib)
Affinity DataIC50: 0.130nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50328584(1-(4-(4-Propionylpiperazin-1-yl)-3-(trifluoromethy...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50641312(CHEMBL5570690)
Affinity DataIC50: 4.80nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50562615(CHEMBL4764756)
Affinity DataIC50: 5.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase mTOR(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 9.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50562615(CHEMBL4764756)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50130694(CHEMBL3416305)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM30641(US8853193, 32-26)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM50641312(CHEMBL5570690)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM31767(3-(4-morpholinopyrido[2,3]furo[2,4-b]pyrimidin-2-y...)
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50641309(CHEMBL5572730)
Affinity DataIC50: 22nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM30641(US8853193, 32-26)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex subunit LST8(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM259272(US9499547, 13)
Affinity DataIC50: 40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 58nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetTarget of rapamycin complex 2 subunit MAPKAP1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50641309(CHEMBL5572730)
Affinity DataIC50: 65nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM400813(QL-X-138 | US10000483, Compound II-6)
Affinity DataIC50: 107nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50130694(CHEMBL3416305)
Affinity DataIC50: 116nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM259272(US9499547, 13)
Affinity DataIC50: 904nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM36409(CID24905147 | 2-(4-amino-1-isopropyl-1H-pyrazolo[3...)
Affinity DataIC50: 2.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM259272(US9499547, 13)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50641310(CHEMBL5594869)
Affinity DataIC50: 1.35E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetEukaryotic initiation factor 4A-I(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM50641311(CHEMBL5542372)
Affinity DataIC50: 1.64E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Shandong University

Curated by ChEMBL
LigandPNGBDBM315499(US10172858, Table 1.22)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM315499(US10172858, Table 1.22)
Affinity DataKi:  152nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM315499(US10172858, Table 1.22)
Affinity DataKi:  165nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM315499(US10172858, Table 1.22)
Affinity DataKi:  4.70E+3nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed