Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50022366
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM496902(PF-07321332 | science.abl4784, 6 | WO2021250648, E...)
Affinity DataKi:  3nMAssay Description:Binding affinity to SARS-Cov-2 main protease assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651461(CHEMBL5631689)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 main protease expressed in Escherichia coli preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651460(CHEMBL5631306)
Affinity DataIC50: 53nMAssay Description:Inhibition of recombinant full length SARS-CoV-2 main protease expressed in Escherichia coli preincubated for 10 mins followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651474(CHEMBL5631518)
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651475(CHEMBL5633930)
Affinity DataIC50: 370nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651480(CHEMBL5632811)
Affinity DataIC50: 570nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651481(CHEMBL5633225)
Affinity DataIC50: 700nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651476(CHEMBL5632920)
Affinity DataIC50: 790nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651470(CHEMBL5631538)
Affinity DataIC50: 970nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651472(CHEMBL5632186)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651479(CHEMBL5631290)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651473(CHEMBL5632123)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651467(CHEMBL5632978)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651478(CHEMBL5633196)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651460(CHEMBL5631306)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431275(Mifurol | CARMOFUR | med.21724, Compound 152 | Car...)
Affinity DataIC50: 1.82E+3nMAssay Description:Inhibition of C-terminal his tagged SARS-Cov-2 main proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651469(CHEMBL5632676)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651464(CHEMBL5632782)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651477(CHEMBL5631345)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651466(CHEMBL5629950)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651463(CHEMBL5633928)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651456(CHEMBL5631646)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651459(CHEMBL5631334)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651465(CHEMBL5633832)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651458(CHEMBL5632793)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651462(CHEMBL5632889)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651457(CHEMBL5633197)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651468(CHEMBL5632482)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651461(CHEMBL5631689)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651454(CHEMBL5631415)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431275(Mifurol | CARMOFUR | med.21724, Compound 152 | Car...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651455(CHEMBL5631416)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50651471(CHEMBL5633371)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431272(CHEMBL2333032 | US9428465, 3)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431270(CHEMBL2333034)
Affinity DataIC50: 6.20E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431271(CHEMBL2333033 | US9428465, 4)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431262(CHEMBL2333042 | US9428465, 5)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431273(CHEMBL2333031)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Gwangju Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50431274(CHEMBL2333065)
Affinity DataIC50: 9.80E+3nMAssay Description:Inhibition of recombinant full length his tagged C-terminal SARS-CoV 2 main protease (M1 to Q307 residues) expressed in Escherichia coli BL21 (DE3) c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
TBA
Entry Details
PubMed