Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019312
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617989(CHEMBL5401589)
Affinity DataKd:  4.60E+3nMAssay Description:Binding affinity to CRM1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617990(CHEMBL5401620)
Affinity DataKd:  5.90E+3nMAssay Description:Binding affinity to CRM1 (unknown origin) assessed as dissociation constant by microscale thermophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617989(CHEMBL5401589)
Affinity DataIC50: 270nMAssay Description:Inhibition of CRM1 nuclear export in human HeLa cells assessed as CRM1 depletion measured after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617989(CHEMBL5401589)
Affinity DataIC50: 280nMAssay Description:Inhibition of CRM1-mediated nuclear export in human HeLa cells expressing mCherry-tagged NES reporter incubated for 3 hrs by confocal microscopy anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617991(CHEMBL5437643)
Affinity DataIC50: 340nMAssay Description:Inhibition of CRM1-mediated nuclear export in human HeLa cells expressing mCherry-tagged NES reporter incubated for 3 hrs by confocal microscopy anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetExportin-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50617991(CHEMBL5437643)
Affinity DataIC50: 550nMAssay Description:Inhibition of CRM1 nuclear export in human HeLa cells assessed as CRM1 depletion measured after 6 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed