Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50020264
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataKd:  188nMAssay Description:Binding affinity to N-terminal/C-terminal FLAG/6His-tagged human PRMT9 (2 to 845 residues) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 540nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT7 (2 to 692 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598015(CHEMBL5199380)
Affinity DataIC50: 890nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of N-terminal/C-terminal human recombinant full-length FLAG-tagged PRMT5 (2 to 637 residues)/C-terminal human His-tagged MEP50 (2 to 342 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628240(CHEMBL5406557)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598020(CHEMBL5202088)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598019(CHEMBL5186617)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598016(CHEMBL5170047)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 1.46E+3nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT4 (2 to 608 residues) using histone H3.3 as substrate and 3H-SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 1.97E+3nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT8 (61 to 394 residues) using histone H4 as substrate and 3H-SAM as c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 7(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT7 (2 to 692 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598017(CHEMBL5206272)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598022(CHEMBL5173678)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of N-terminal/C-terminal human recombinant full-length FLAG-tagged PRMT5 (2 to 637 residues)/C-terminal human His-tagged MEP50 (2 to 342 r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 9(Homo sapiens)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50598021(CHEMBL5191769)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant PRMT9 using biotinylated SF3B2(500 to 519 residues) as substrate and SAM as cosubstrate pre-incubated with compound f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT3 (2 to 531 residues) using histone H4 as substrate and 3H-SAM as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetHistone-arginine methyltransferase CARM1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT4 (2 to 608 residues) using histone H3.3 as substrate and 3H-SAM as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 8(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT8 (61 to 394 residues) using histone H4 as substrate and 3H-SAM as c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT1 (2 to 371 residues) using histone H4 as substrate and 3H-SAM as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628242(CHEMBL5396270)
Affinity DataIC50: 4.97E+4nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT6 (2 to 375 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 6(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT6 (2 to 375 residues) using histone GST-GAR as substrate and 3H-SAM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 1(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal/C-terminal GST-tagged human recombinant full-length PRMT1 (2 to 371 residues) using histone H4 as substrate and 3H-SAM as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetProtein arginine N-methyltransferase 3(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50628241(CHEMBL5408585)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of N-terminal/C-terminal His-tagged human recombinant full-length PRMT3 (2 to 531 residues) using histone H4 as substrate and 3H-SAM as co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed