Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50020814
TargetD(2) dopamine receptor(Rat)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50633730(CHEMBL5435489)
Affinity DataIC50: 7.50E+4nMAssay Description:Displacement of [3H]-raclopride from rat brain striatum dopamine D2 receptor incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50633730(CHEMBL5435489)
Affinity DataIC50: 1.80E+5nMAssay Description:Displacement of [3H]-ketanserin from rat brain cortex 5-HT2A receptor incubated for 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1 hr by TopCount l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50160434(AM630 | (6-iodo-2-methyl-1-(2-morpholinoethyl)-1H-...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1 hr by TopCount l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50633732(CHEMBL5483080)
Affinity DataKi:  990nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1 hr by TopCount l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50633731(CHEMBL3586094)
Affinity DataKi:  8.19E+3nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1 hr by TopCount l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetCannabinoid receptor 2(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50633730(CHEMBL5435489)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [3H]-CP55940 from human CB2 receptor expressed in CHO cell membranes assessed as inhibition constant incubated for 1 hr by TopCount l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed