Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50019572
TargetProgrammed cell death 1 ligand 1(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620625(CHEMBL5439087)
Affinity DataKd:  27nMAssay Description:Binding affinity to human PD-L1 (18 to 134 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620626(CHEMBL5399538)
Affinity DataKd:  8nMAssay Description:Binding affinity to human PD-L1 (18 to 134 residues) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by MST assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620625(CHEMBL5439087)
Affinity DataEC50:  2.70E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells cocultured with artificial antigen presenting cells assessed as increase in TCR-mediated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620626(CHEMBL5399538)
Affinity DataEC50:  880nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells cocultured with artificial antigen presenting cells assessed as increase in TCR-mediated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataEC50:  1.57E+3nMAssay Description:Inhibition of PD-1/PD-L1 interaction in human Jurkat T cells cocultured with artificial antigen presenting cells assessed as increase in TCR-mediated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620626(CHEMBL5399538)
Affinity DataIC50: 2nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as induction of PD-L1 dimerization incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50239948(US9850225, Example 1166 | CHEMBL4071326)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as induction of PD-L1 dimerization incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University Medical Center Groningen

Curated by ChEMBL
LigandPNGBDBM50620625(CHEMBL5439087)
Affinity DataIC50: 5nMAssay Description:Inhibition of human PD-1/PD-L1 interaction assessed as induction of PD-L1 dimerization incubated for 2 hrs by HTRF analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed