Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50019884
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624182(CHEMBL5433278)
Affinity DataKd:  55nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624183(CHEMBL5394570)
Affinity DataKd:  1.40nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624184(CHEMBL5415331)
Affinity DataKd:  11nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624185(CHEMBL5439046)
Affinity DataKd:  0.900nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624183(CHEMBL5394570)
Affinity DataKd:  6.90nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624184(CHEMBL5415331)
Affinity DataKd:  57nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624185(CHEMBL5439046)
Affinity DataKd:  7nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624185(CHEMBL5439046)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624185(CHEMBL5439046)
Affinity DataKi:  7nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624186(CHEMBL5408686)
Affinity DataKi:  8nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624186(CHEMBL5408686)
Affinity DataKi:  13nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624182(CHEMBL5433278)
Affinity DataKi:  26nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDM2 (17 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Aileron Therapeutics

Curated by ChEMBL
LigandPNGBDBM50624182(CHEMBL5433278)
Affinity DataKi:  106nMAssay Description:Binding affinity to 6x-His-TEV-tagged human MDMX (15 to 111 residues) assessed as inhibition constant by SPR analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed