Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50019568
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataEC50:  4.17E+4nMAssay Description:Negative allosteric modulation of mu opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620606(CHEMBL5431714)
Affinity DataIC50: 21nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620603(CHEMBL499322)
Affinity DataIC50: 90nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620608(CHEMBL5413536)
Affinity DataIC50: 137nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50587998(CHEMBL5190596)
Affinity DataIC50: 173nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620612(CHEMBL5435537)
Affinity DataIC50: 190nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620614(CHEMBL5413043)
Affinity DataIC50: 242nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataIC50: 311nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation incubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620609(CHEMBL5436233)
Affinity DataIC50: 349nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620610(CHEMBL5408683)
Affinity DataIC50: 499nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620611(CHEMBL5398409)
Affinity DataIC50: 556nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50532215(CBD-V | CBDV | Cannabidivarin | GWP42006)
Affinity DataIC50: 556nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620605(CHEMBL5402755)
Affinity DataIC50: 619nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 722nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620604(CHEMBL5435390)
Affinity DataIC50: 1.17E+3nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620607(CHEMBL5433984)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50620613(CHEMBL5406692)
Affinity DataIC50: 1.40E+3nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50318484(CHEMBL190461 | 2-((1R,6R)-6-Isopropenyl-3-methyl-c...)
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Indiana University

Curated by ChEMBL
LigandPNGBDBM50587997(CHEMBL5184521)
Affinity DataIC50: 6.50E+3nMAssay Description:Negative allosteric modulation of human mu opioid receptor expressed in HEK293 cells assessed as increase in cAMP accumulation in presence of fentany...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed