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Report error Found 81 Enz. Inhib. hit(s) with all data for entry = 50019561
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in pathHunter cells assessed as beta-arrestin translocation activity incubated for 90 to 180...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620557(CHEMBL5429932)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in pathHunter cells assessed as beta-arrestin translocation activity incubated for 90 to 180...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  1.60nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK-T cells assessed as cAMP production incubated for 30 mins in the presence of NKH-477 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620534(CHEMBL5435602)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as cAMP production incubated for 15 mins by luciferase based Glosens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as cAMP production incubated for 15 mins by luciferase based Glosens...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620557(CHEMBL5429932)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in HEK-T cells assessed as cAMP production incubated for 30 mins in the presence of NKH-477 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620534(CHEMBL5435602)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at N-terminal Flag epitope tagged human dopamine D1 receptor expressed in HTLA cells assessed as beta-arrestin translocation activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM86282(NSC_1218 | cid_11957706 | 6-Chloro-1-phenyl-2,3,4,...)
Affinity DataEC50:  1.78E+3nMAssay Description:Agonist activity at N-terminal Flag epitope tagged human dopamine D1 receptor expressed in HTLA cells assessed as beta-arrestin translocation activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 0.370nMAssay Description:Antagonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as inhibition of dopamine-induced cAMP production incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK-T cells assessed as inhibition of dopamine-induced cAMP production preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in pathHunter cells assessed as inhibition of dopamine-induced beta-arrestin translocatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620557(CHEMBL5429932)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in HEK-T cells assessed as inhibition of dopamine-induced cAMP production preincubated fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620534(CHEMBL5435602)
Affinity DataIC50: 107nMAssay Description:Antagonist activity at human dopamine D1 receptor expressed in HEK-T cells assessed as inhibition of dopamine-induced cAMP production incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620557(CHEMBL5429932)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human dopamine D3 receptor expressed in pathHunter cells assessed as inhibition of dopamine-induced beta-arrestin translocatio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM82247(SCH 23390,R(+) | CAS_87134-87-0 | CHEMBL2158641 | ...)
Affinity DataIC50: 162nMAssay Description:Antagonist activity at N-terminal Flag epitope tagged human dopamine D1 receptor expressed in HTLA cells assessed as inhibition of dopamine-induced b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620534(CHEMBL5435602)
Affinity DataIC50: 1.82E+3nMAssay Description:Antagonist activity at N-terminal Flag epitope tagged human dopamine D1 receptor expressed in HTLA cells assessed as inhibition of dopamine-induced b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50008735(CHEMBL8514 | BUTACLAMOL,d- | (+)-3-(tert-butyl)-(3...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50378584(STEPHOLIDINE)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620534(CHEMBL5435602)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(2) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D2 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50001888([3-(2-Chloro-phenothiazin-10-yl)-propyl]-dimethyl-...)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620552(CHEMBL5439212)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620529(CHEMBL5410387)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620528(CHEMBL5433001)
Affinity DataKi:  17nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620546(CHEMBL5436253)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620535(CHEMBL5402269)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620532(CHEMBL5410716)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50378584(STEPHOLIDINE)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620536(CHEMBL5416700)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620531(CHEMBL5399568)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620531(CHEMBL5399568)
Affinity DataKi:  33nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620533(CHEMBL5428803)
Affinity DataKi:  34nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620528(CHEMBL5433001)
Affinity DataKi:  40nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620532(CHEMBL5410716)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620540(CHEMBL5395272)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620529(CHEMBL5410387)
Affinity DataKi:  46nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620530(CHEMBL5399166)
Affinity DataKi:  51nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620530(CHEMBL5399166)
Affinity DataKi:  53nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620541(CHEMBL5438487)
Affinity DataKi:  58nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620557(CHEMBL5429932)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620542(CHEMBL5425375)
Affinity DataKi:  68nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620537(CHEMBL5423880)
Affinity DataKi:  79nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620551(CHEMBL5394838)
Affinity DataKi:  85nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620533(CHEMBL5428803)
Affinity DataKi:  86nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620553(CHEMBL5399422)
Affinity DataKi:  87nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(3) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620552(CHEMBL5439212)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]N-methylspiperone from human dopamine D3 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620539(CHEMBL5420387)
Affinity DataKi:  91nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620548(CHEMBL5412881)
Affinity DataKi:  108nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620538(CHEMBL5398357)
Affinity DataKi:  111nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
City University of New York

Curated by ChEMBL
LigandPNGBDBM50620547(CHEMBL5399393)
Affinity DataKi:  147nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
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