Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50019429
TargetCyclic GMP-AMP synthase(Mouse)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50509050(CHEMBL4438309)
Affinity DataIC50: 270nMAssay Description:Inhibition of mouse cGAS by ATP consumption assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCyclic GMP-AMP synthase(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50582695(CHEMBL5094220)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of N-terminal 6His-SUMO2 fusion protein tagged full length human cGAS (1 to 522 residues) expressed in Escherichia coli Rosetta 2 (DE3) ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetStimulator of interferon genes protein(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50576528(CHEMBL4859961)
Affinity DataIC50: 1.07E+4nMAssay Description:Displacement of F-c-di-GMP from human STING expressed in Escherichia coli Rosetta 2(pLysS) cells at 20 uM incubated for 5 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed