Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50019427
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619122(CHEMBL5433070)
Affinity DataIC50: 130nMAssay Description:Inhibition of Staphylococcus aureus DHFR preincubated for 5 mins followed by dihydrofolic acid addition and measured for 10 mins by absorbance based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619121(CHEMBL5435219)
Affinity DataIC50: 170nMAssay Description:Inhibition of Staphylococcus aureus DHFR preincubated for 5 mins followed by dihydrofolic acid addition and measured for 10 mins by absorbance based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619120(CHEMBL5437108)
Affinity DataIC50: 230nMAssay Description:Inhibition of Staphylococcus aureus DHFR preincubated for 5 mins followed by dihydrofolic acid addition and measured for 10 mins by absorbance based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDihydrofolate reductase(Staphylococcus aureus)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM66082(SMR000449324 | MLS001401431 | (2S)-2-[[4-[[2,4-bis...)
Affinity DataIC50: 360nMAssay Description:Inhibition of Staphylococcus aureus DHFR preincubated for 5 mins followed by dihydrofolic acid addition and measured for 10 mins by absorbance based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins in presence of relaxed plasmid DNA by supercoiling based gel electrophoresis ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619122(CHEMBL5433070)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins in presence of relaxed plasmid DNA by supercoiling based gel electrophoresis ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619121(CHEMBL5435219)
Affinity DataIC50: 1.37E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins in presence of relaxed plasmid DNA by supercoiling based gel electrophoresis ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619120(CHEMBL5437108)
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of Staphylococcus aureus DNA gyrase incubated for 30 mins in presence of relaxed plasmid DNA by supercoiling based gel electrophoresis ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM21690(Ciprinol | 1-cyclopropyl-6-fluoro-4-oxo-7-(piperaz...)
Affinity DataIC50: 2.54E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled plasmid DNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619122(CHEMBL5433070)
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled plasmid DNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619120(CHEMBL5437108)
Affinity DataIC50: 6.87E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled plasmid DNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Vietnam National University

Curated by ChEMBL
LigandPNGBDBM50619121(CHEMBL5435219)
Affinity DataIC50: 7.92E+4nMAssay Description:Inhibition of Staphylococcus aureus DNA topoisomerase 4 using supercoiled plasmid DNA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed