Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50019388
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618713(CHEMBL5425421)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of ATX (unknown origin) using lysoPLD as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM555294(BDBM50540913 | 34(6-chloro-2-cyclopropyl-1-(1-(eth...)
Affinity DataIC50: 2nMAssay Description:Inhibition of ATX (unknown origin) using lysoPLD as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618714(CHEMBL5430413)
Affinity DataIC50: 2nMAssay Description:Inhibition of human ATX using LPC as substrate assessed as choline release measured after 1.5 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50187690(CHEMBL3827088)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ATX (unknown origin) using FS-3 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618715(CHEMBL5439867)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of ATX (unknown origin) using FS-3 as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618713(CHEMBL5425421)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of ATX in human bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM555294(BDBM50540913 | 34(6-chloro-2-cyclopropyl-1-(1-(eth...)
Affinity DataIC50: 9.70nMAssay Description:Inhibition of ATX in human bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618712(CHEMBL5414051)
Affinity DataIC50: 21nMAssay Description:Inhibition of human ATX using FS-3 as substrate measured after 1 hrs by fluorescence based choline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618713(CHEMBL5425421)
Affinity DataIC50: 22nMAssay Description:Inhibition of ATX in mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618712(CHEMBL5414051)
Affinity DataIC50: 23nMAssay Description:Inhibition of human ATX using LPC as substrate measured after 2 hrs by fluorescence based choline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50322724(3-[(4-{[3-(4-Fluorobenzyl)-2,4-dioxo-1,3-thiazolan...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human ATX by using LPC as substrate by choline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50187687(CHEMBL3828733 | US11124490, Compound 918013)
Affinity DataIC50: 44nMAssay Description:Inhibition of human ATX using LPC as substrate measured after 2 hrs by fluorescence based choline release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 2(Mouse)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM555294(BDBM50540913 | 34(6-chloro-2-cyclopropyl-1-(1-(eth...)
Affinity DataIC50: 62nMAssay Description:Inhibition of ATX in mouse plasmaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618709(CHEMBL5434693)
Affinity DataIC50: 134nMAssay Description:Inhibition of human ATX using LPC as substrate preincubated for 30 mins followed by substrate addition measured after 90 mins by choline release assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618711(CHEMBL5395463)
Affinity DataIC50: 218nMAssay Description:Inhibition of recombinant human ATX expressed in Sf9 cells using FS-3 as substrate measured after 1 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetAutotaxin(Human)
Weifang Medical University

Curated by ChEMBL
LigandPNGBDBM50618710(CHEMBL5438529)
Affinity DataIC50: 219nMAssay Description:Inhibition of recombinant human ATX expressed in Sf9 cells using FS-3 as substrate measured after 1 hrs by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed