Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50019387
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50323460(N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthoh...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataKd:  6.10nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50323460(N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthoh...)
Affinity DataKd:  4.20nMAssay Description:Binding affinity to human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as dissociation constant by Surface pl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataIC50: 560nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM58490(SMR000466355 | (7S,9S)-9-acetyl-7-[(2R,4S,5S,6S)-4...)
Affinity DataIC50: 610nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618707(PIRARUBICIN | Pirarubicin | Pirarubicine | Pirarub...)
Affinity DataIC50: 790nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618706(CHEMBL5394285)
Affinity DataIC50: 990nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50240819(CHEMBL4084119)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618705(CHEMBL5437637)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50242279(corilagin | 6,7,8,11,12,13,22,23-octahydroxy-3,16-...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50242188(6-{8(Z)-pentadecenyl}salicylic acid | Anacardic ac...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50594731(CHEMBL1241028)
Affinity DataIC50: 1.84E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50236531((2S,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3...)
Affinity DataIC50: 1.99E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCrossover junction endonuclease MUS81(Homo sapiens)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50618708(CHEMBL4071130)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE2 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Fuzhou University

Curated by ChEMBL
LigandPNGBDBM50019324(CHEMBL3289398)
Affinity DataIC50: 3.33E+3nMAssay Description:Inhibition of human GST-tagged MUS81-ECE1 expressed in Escherichia coli BL21(DE3)Rosetta2 cells incubated for 15 mins by FRET based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed