Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50019547
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50217439(cis-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]ben...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620382(CHEMBL5411340)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620379(CHEMBL5438483)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620380(CHEMBL5405712)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620384(CHEMBL5426753)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620386(CHEMBL5420193)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620368(CHEMBL5408127)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50191854(N-(1-acetyl-piperidin-4-yl)-N'-(adamantan-1-yl)ure...)
Affinity DataIC50: 8nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620374(CHEMBL5415470)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620381(CHEMBL5395369)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620383(CHEMBL5407621)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620372(CHEMBL5428089)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620370(CHEMBL5435336)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620387(CHEMBL5418650)
Affinity DataIC50: 20nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620369(CHEMBL5410246)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620378(CHEMBL5411642)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620385(CHEMBL5406849)
Affinity DataIC50: 27nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620375(CHEMBL5411847)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620371(CHEMBL5439306)
Affinity DataIC50: 53nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50591532(CHEMBL4590950)
Affinity DataIC50: 61nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50: 69nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620368(CHEMBL5408127)
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620373(CHEMBL5415175)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620374(CHEMBL5415470)
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50591533(CHEMBL4449485)
Affinity DataIC50: 100nMAssay Description:Inhibition of sEH (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620375(CHEMBL5411847)
Affinity DataIC50: 148nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620367(CHEMBL5402713)
Affinity DataIC50: 171nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50591533(CHEMBL4449485)
Affinity DataIC50: 180nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620368(CHEMBL5408127)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50591532(CHEMBL4590950)
Affinity DataIC50: 280nMAssay Description:Inhibition of 5-LOX (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620373(CHEMBL5415175)
Affinity DataIC50: 285nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620377(CHEMBL5437647)
Affinity DataIC50: 288nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620382(CHEMBL5411340)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620376(CHEMBL5402379)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620377(CHEMBL5437647)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620378(CHEMBL5411642)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620379(CHEMBL5438483)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620380(CHEMBL5405712)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620381(CHEMBL5395369)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620369(CHEMBL5410246)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620383(CHEMBL5407621)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620384(CHEMBL5426753)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620370(CHEMBL5435336)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620371(CHEMBL5439306)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620385(CHEMBL5406849)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620372(CHEMBL5428089)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620386(CHEMBL5420193)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620387(CHEMBL5418650)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21(DE3) assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620367(CHEMBL5402713)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant sEH expressed in baculovirus infected Sf9 insect cells assessed as reduction in 6-methoxynaphthaldehyde formation usi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50620367(CHEMBL5402713)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of 5-LOX in human PMNL assessed as reduction in all-trans isomers of LTB4 and 5-HETE formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
Displayed 1 to 50 (of 56 total ) | Next | Last >>
Jump to: