Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50019259
TargetProtein Mdm4(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617216(CHEMBL5410760)
Affinity DataIC50: 9nMAssay Description:Inhibition of human MDM4 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617216(CHEMBL5410760)
Affinity DataIC50: 9nMAssay Description:Inhibition of human MDM2 incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetProtein Mdm4(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617215(CHEMBL5395151)
Affinity DataIC50: 43nMAssay Description:Inhibition of human MDM4 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617215(CHEMBL5395151)
Affinity DataIC50: 43nMAssay Description:Inhibition of human MDM2 incubated for 1 hrs by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617218(CHEMBL5425065)
Affinity DataIC50: 90nMAssay Description:Displacement of FAM labeled p53 fragment from human MDM2 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Unnatural Products

Curated by ChEMBL
LigandPNGBDBM50617217(CHEMBL5434688)
Affinity DataIC50: 8.10E+3nMAssay Description:Displacement of FAM labeled p53 fragment from human MDM2 (1 to 116 residues) incubated for 1 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed