Compile Data Set for Download or QSAR
Report error Found 84 Enz. Inhib. hit(s) with all data for entry = 50019375
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618668(CHEMBL5424250)
Affinity DataIC50: 0.590nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50230552(CHEMBL5267731)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618670(CHEMBL5406867)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618664(CHEMBL5436337)
Affinity DataIC50: 4nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618667(CHEMBL5401833)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618672(CHEMBL5434496)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618677(CHEMBL5395662)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618679(CHEMBL5430097)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618665(CHEMBL5429762)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618667(CHEMBL5401833)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618665(CHEMBL5429762)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618664(CHEMBL5436337)
Affinity DataIC50: 13nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618664(CHEMBL5436337)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618665(CHEMBL5429762)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618666(CHEMBL5428131)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618665(CHEMBL5429762)
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618670(CHEMBL5406867)
Affinity DataIC50: 25nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618664(CHEMBL5436337)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618672(CHEMBL5434496)
Affinity DataIC50: 26nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618671(CHEMBL5419103)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618666(CHEMBL5428131)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618673(CHEMBL5406674)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50230552(CHEMBL5267731)
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618668(CHEMBL5424250)
Affinity DataIC50: 34nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618667(CHEMBL5401833)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618666(CHEMBL5428131)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618668(CHEMBL5424250)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618679(CHEMBL5430097)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618667(CHEMBL5401833)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618670(CHEMBL5406867)
Affinity DataIC50: 41nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618664(CHEMBL5436337)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618678(CHEMBL5413782)
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50230552(CHEMBL5267731)
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618674(CHEMBL5420372)
Affinity DataIC50: 80nMAssay Description:Inhibition of human recombinant MMP-2 (34 to 660 residues) expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618679(CHEMBL5430097)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618673(CHEMBL5406674)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 87nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618666(CHEMBL5428131)
Affinity DataIC50: 89nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618668(CHEMBL5424250)
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618672(CHEMBL5434496)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618679(CHEMBL5430097)
Affinity DataIC50: 93nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618677(CHEMBL5395662)
Affinity DataIC50: 95nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618670(CHEMBL5406867)
Affinity DataIC50: 96nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618670(CHEMBL5406867)
Affinity DataIC50: 101nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618665(CHEMBL5429762)
Affinity DataIC50: 102nMAssay Description:Inhibition of human recombinant MMP-9 (20 to 707 residues) Gln279Arg mutant expressed in CHO cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618673(CHEMBL5406674)
Affinity DataIC50: 104nMAssay Description:Inhibition of human recombinant MMP-13 (20 to 471 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dini...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618669(CHEMBL5396285)
Affinity DataIC50: 105nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetMacrophage metalloelastase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50618677(CHEMBL5395662)
Affinity DataIC50: 113nMAssay Description:Inhibition of human recombinant MMP-12 (17 to 470 residues) Val97Leu mutant expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Munster

Curated by ChEMBL
LigandPNGBDBM50230552(CHEMBL5267731)
Affinity DataIC50: 149nMAssay Description:Inhibition of human recombinant MMP-8 (21 to 467 residues) expressed in NS0 cells using (7-methoxycoumarin-4-y1)-acetyl-Pro-Leu-Gly-Leu-[3-(2,4-dinit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
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