Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50019724
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50513866(CHEMBL4450810)
Affinity DataIC50: 8.80nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622314(CHEMBL5398699)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622319(CHEMBL5417718)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622317(CHEMBL5395126)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622320(CHEMBL5437385)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622318(CHEMBL5413413)
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 12nMAssay Description:Inhibition of partial length human ZAK by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLIM domain kinase 1(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length human LIMK1 by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetLIM domain kinase 2(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 21nMAssay Description:Inhibition of full length human LIMK2 by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase kinase kinase 20(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622316(CHEMBL5411306)
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant ZAK (unknown origin) using ATP as substrate preincubated for 60 mins followed by substrate addition and measured after 40 m...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Lck(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 204nMAssay Description:Inhibition of partial length human LCK by KINOMEscan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622320(CHEMBL5437385)
Affinity DataIC50: 247nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin) incubated for 1 hr in presence of ATP by envision multilabel reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50513866(CHEMBL4450810)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin) incubated for 1 hr in presence of ATP by envision multilabel reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Jinan University

Curated by ChEMBL
LigandPNGBDBM50622315(CHEMBL5436237)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of B-RAF V600E mutant (unknown origin) incubated for 1 hr in presence of ATP by envision multilabel reader analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed