Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50020415
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629759BDBM50629759(CHEMBL5418829)
Affinity DataEC50:  30nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629767BDBM50629767(CHEMBL5425099)
Affinity DataEC50:  32nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629761BDBM50629761(CHEMBL5411493)
Affinity DataEC50:  33nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629758BDBM50629758(CHEMBL5413077)
Affinity DataEC50:  37nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629764BDBM50629764(CHEMBL5402606)
Affinity DataEC50:  49nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629771BDBM50629771(CHEMBL5394925)
Affinity DataEC50:  51nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629749BDBM50629749(CHEMBL5429249)
Affinity DataEC50:  58nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629773BDBM50629773(CHEMBL5419884)
Affinity DataEC50:  75nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629748BDBM50629748(CHEMBL5411501)
Affinity DataEC50:  76nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629762BDBM50629762(CHEMBL5396065)
Affinity DataEC50:  93nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629754BDBM50629754(CHEMBL5412602)
Affinity DataEC50:  107nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629744BDBM50629744(CHEMBL5418586)
Affinity DataEC50:  115nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629752BDBM50629752(CHEMBL5412220)
Affinity DataEC50:  130nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629743BDBM50629743(CHEMBL5430306)
Affinity DataEC50:  146nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629755BDBM50629755(CHEMBL5408542)
Affinity DataEC50:  174nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629770BDBM50629770(CHEMBL5399310)
Affinity DataEC50:  189nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629757BDBM50629757(CHEMBL5437238)
Affinity DataEC50:  194nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629772BDBM50629772(CHEMBL5434521)
Affinity DataEC50:  214nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629753BDBM50629753(CHEMBL5423361)
Affinity DataEC50:  231nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629745BDBM50629745(CHEMBL5405761)
Affinity DataEC50:  245nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629768BDBM50629768(CHEMBL5437229)
Affinity DataEC50:  248nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629756BDBM50629756(CHEMBL5395125)
Affinity DataEC50:  275nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629746BDBM50629746(CHEMBL5417522)
Affinity DataEC50:  316nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629766BDBM50629766(CHEMBL5397794)
Affinity DataEC50:  400nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629738BDBM50629738(CHEMBL3605322)
Affinity DataEC50:  625nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629769BDBM50629769(CHEMBL5394547)
Affinity DataEC50:  749nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629747BDBM50629747(CHEMBL5400374)
Affinity DataEC50:  801nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629750BDBM50629750(CHEMBL5422343)
Affinity DataEC50:  824nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50073654BDBM50073654(CHEBI:47807 | 4-(Methylsulfinyl)Butyl Isothiocyana...)
Affinity DataEC50:  879nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629765BDBM50629765(CHEMBL5407290)
Affinity DataEC50:  914nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629751BDBM50629751(CHEMBL5427217)
Affinity DataEC50:  1.22E+3nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629760BDBM50629760(CHEMBL5415245)
Affinity DataEC50:  1.31E+3nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629763BDBM50629763(CHEMBL5430569)
Affinity DataEC50:  1.87E+3nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50504654BDBM50504654(CHEBI:76004 | AZL 0 211089 | AZL O 211089 | AZL-02...)
Affinity DataEC50:  5.11E+3nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629739BDBM50629739(CHEMBL5413964)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629742BDBM50629742(CHEMBL5423948)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50342426BDBM50342426(4-methoxy-4-oxobut-2-enoic acid | methyl fumarate ...)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629740BDBM50629740(CHEMBL5434926)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
Korea Institute of Science and Technology (KIST)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50629741BDBM50629741(CHEMBL5415569)
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of Nrf2 in human U2OS cells co-expressing Keap1 assessed as induction of Nrf2 nuclear translocation incubated for 6 hrs by PathHunter chem...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed