Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50020406
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 0.920nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50601534(CHEMBL4539742)
Affinity DataIC50: 1nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 3nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 3nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192714(YKL-05-095 (3) | US11725011, Compound YKL-05-95)
Affinity DataIC50: 6nMAssay Description:Inhibition of recombinant human SIK2 by caliper based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629708(CHEMBL5438704)
Affinity DataIC50: 6nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50601534(CHEMBL4539742)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 6.60nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629709(CHEMBL5408557)
Affinity DataIC50: 8nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192712(HG-9-91-01 (1))
Affinity DataIC50: 9.60nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618894(CHEMBL5393771)
Affinity DataIC50: 10nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618894(CHEMBL5393771)
Affinity DataIC50: 10nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192716(YKL-05-099 (5) | US11725011, Compound YKL-05-99)
Affinity DataIC50: 10nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM13216(N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyeth...)
Affinity DataIC50: 10nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50622916(CHEMBL5305160)
Affinity DataIC50: 12nMAssay Description:Inhibition of SIK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629708(CHEMBL5438704)
Affinity DataIC50: 16nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM4552(CHEMBL288441 | SKI-606 | 4-[(2,4-Dichloro-5-methox...)
Affinity DataIC50: 18nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50601534(CHEMBL4539742)
Affinity DataIC50: 22nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629709(CHEMBL5408557)
Affinity DataIC50: 24nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192716(YKL-05-099 (5) | US11725011, Compound YKL-05-99)
Affinity DataIC50: 30nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM192716(YKL-05-099 (5) | US11725011, Compound YKL-05-99)
Affinity DataIC50: 40nMAssay Description:Inhibition of recombinant human SIK2 by caliper based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50622916(CHEMBL5305160)
Affinity DataIC50: 43nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629708(CHEMBL5438704)
Affinity DataIC50: 51nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50618894(CHEMBL5393771)
Affinity DataIC50: 100nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50622916(CHEMBL5305160)
Affinity DataIC50: 110nMAssay Description:Inhibition of SIK1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPDBSimilars
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50629709(CHEMBL5408557)
Affinity DataIC50: 146nMAssay Description:Inhibition of SIK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed