Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50019704
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622045(CHEMBL5412452)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetInterstitial collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-1 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622045(CHEMBL5412452)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622045(CHEMBL5412452)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50102750(CHEMBL3359091)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622039(CHEMBL5400739)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human recombinant MMP-9 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
Target72 kDa type IV collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of human recombinant MMP-2 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622045(CHEMBL5412452)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 48nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622048(CHEMBL5407407)
Affinity DataIC50: 52nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetStromelysin-2(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50063917(CHEMBL279785 | marimastat | cid_119031 | (2S,3R)-N...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human recombinant MMP-10 using Mca-Aug-Pro-Lys-Pro-Val-Glu-Nval-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 30 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622038(CHEMBL5400805)
Affinity DataIC50: 106nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622042(CHEMBL5416182)
Affinity DataIC50: 113nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622036(CHEMBL5411757)
Affinity DataIC50: 118nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622046(CHEMBL5434802)
Affinity DataIC50: 127nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622035(CHEMBL5418737)
Affinity DataIC50: 149nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCollagenase 3(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622037(CHEMBL5408518)
Affinity DataIC50: 313nMAssay Description:Inhibition of human recombinant MMP-13 using Mca-Lys-Pro-Leu-GlyLeu-Dpa-Ala-Arg-NH2 as substrate preincubated for 30 mins followed by substrate addit...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622043(CHEMBL5426756)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622047(CHEMBL5400294)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622040(CHEMBL5394834)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622044(CHEMBL5413816)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNeutrophil collagenase(Human)
University of Ottawa

Curated by ChEMBL
LigandPNGBDBM50622041(CHEMBL4859817)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant MMP-8 incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
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