Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50020393
Affinity DataIC50: 2.5nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of EZH2 methyltransferase activity in human PA-1 cells assessed as reduction in H3K27me3 level measured after 4 days by Western blot analy...More data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of wildtype EZH2 (unknown origin) by AlphaLISA methyltransferase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of wildtype EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of EZH2 (unknown origin) by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of wild type EZH2 (unknown origin) by AlphaLISA assayMore data for this Ligand-Target Pair
Affinity DataIC50: 8.40nMAssay Description:Inhibition of human EZH1 by radiometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.90nMAssay Description:Inhibition of N-terminal His-tagged EZH2 (unknown origin) expressed in Sf9 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human EZH2 in human MCF-10A cells assessed as reduction in H3K27me3 levels incubated for 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of human EZH2 using core histone as substrate incubated for 1 hr by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of EZH2 (unknown origin) in PRC2 complex using H3 (1 to 24 residues) and 3H-SAM as substrate incubated for 1 hrs by Scintillation proximit...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of N-terminal flag-tagged wildtype human EZH2 Y641F mutant expressed in Sf9 cells incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of EZH2 Y641F mutant (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:Inhibition of N-terminal flag-tagged wildtype human EZH2 expressed in Sf9 cells incubated for 2 hrs by fluorescence based analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of wildtype EZH1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 24nMAssay Description:Inhibition of EZH2 (unknown origin) in PRC2 complex using H3 (1 to 24 residues) and 3H-SAM as substrate incubated for 1 hrs by Scintillation proximit...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of BRD4 (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant full length EZH1 measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 45nMAssay Description:Inhibition of wildtype EZH1 expressed in human MCF-10A cells assessed as reduction in H3K27me3 level incubated for 1 hr by Western blot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 54nMAssay Description:Inhibition of C-terminal recombinant human EZH2More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Inhibition of N-terminal FLAG-tagged recombinant full-length human EZH2 Y641F mutant in PRC2 complex expressed in baculovirus infected Sf9 cells usin...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant EHMT2 G9a using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of EZH2 (unknown origin) using SAM as substrate preincubated for 10 mins followed by substrate addition and measured after 4 hrs by HTRF a...More data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of EZH2 methyltransferase activity in human A2780 cells assessed as reduction in H3K27 level and measured after 96 hrs by Western blot ana...More data for this Ligand-Target Pair
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of EZH2 (unknown origin) using plate-coated histone as substrate at 5 uM incubated for 90 mins in presence of 5 uM SAM by AlphaScreen assa...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 63nMAssay Description:Binding affinity to EZH2 (unknown origin) expressed in baculovirus infected Sf9 cells using H3K27me1 (H2N-RKQLATKAAR Kme1)SAPATGGVKKP-NTPEGBiot) as s...More data for this Ligand-Target Pair
