Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50019695
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 7nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 19nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 19nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 22nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 26nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 30nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 33nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 49nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 54nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 57nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 58nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 71nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 81nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 97nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(malaria parasite P. falciparum)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 103nMAssay Description:Inhibition of recombinant Plasmodium falciparum PNP incubated for 10 minsMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 122nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 134nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 145nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 149nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 153nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 166nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 176nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 251nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 364nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 494nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
The Czech Academy of Sciences
Curated by ChEMBL
The Czech Academy of Sciences
Curated by ChEMBL
Affinity DataIC50: 644nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant PNP incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars
Affinity DataIC50: 709nMAssay Description:Inhibition of human recombinant PNP expressed in Escherichia coli incubated for 10 minsMore data for this Ligand-Target Pair
Ligand InfoSimilars




















3D Structure (crystal)




