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Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50019029
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614739(CHEMBL5289040)
Affinity DataEC50:  81nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataEC50:  3nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells incubated for 1 hr by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50440033(Crolom | Cromoglicic Acid | CROMOLYN)
Affinity DataEC50:  520nMAssay Description:Agonist activity at GPR-35 (unknown origin) expressed in HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at GPR-35 (unknown origin) expressed in HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50440033(Crolom | Cromoglicic Acid | CROMOLYN)
Affinity DataEC50:  7.00E+3nMAssay Description:Agonist activity at GPR-35 (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at GPR-35 (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50612246(ZAPRINAST | Zaprinast | M&B 22948 | NSC-757885)
Affinity DataEC50:  0.710nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614742(CHEMBL5288015)
Affinity DataKd:  18nMAssay Description:Binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells using furimazine as substrate incubated for 30 mins in presence of zaprinast fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataKd:  8.30nMAssay Description:Binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells using furimazine as substrate incubated for 30 mins in presence of zaprinast fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614740(CHEMBL5281778)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells using furimazine as substrate incubated for 30 mins in presence of zaprinast fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614739(CHEMBL5289040)
Affinity DataKd:  7.40nMAssay Description:Binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells using furimazine as substrate incubated for 30 mins in presence of zaprinast fol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614742(CHEMBL5288015)
Affinity DataEC50:  59nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataEC50:  42nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614740(CHEMBL5281778)
Affinity DataEC50:  50nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataIC50: 5.60nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614742(CHEMBL5288015)
Affinity DataIC50: 7.80nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614740(CHEMBL5281778)
Affinity DataIC50: 9.40nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614739(CHEMBL5289040)
Affinity DataIC50: 9.60nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50185(2-hydroxy-4-[[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at GPR-35 (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614743(CID 27456 | CHEMBL1708510)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at GPR-35 (unknown origin) by beta-arrestin assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614741(CHEMBL5285029)
Affinity DataIC50: 398nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614740(CHEMBL5281778)
Affinity DataIC50: 542nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614742(CHEMBL5288015)
Affinity DataIC50: 769nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614739(CHEMBL5289040)
Affinity DataIC50: 1.03E+3nMAssay Description:Agonist activity at GPR-35 in human HT-29 cells assessed as desensitization of zaprinast induced DMR response incubated for 1 hr followed by zaprinas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50185(2-hydroxy-4-[[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop...)
Affinity DataKi:  4nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50575549(CHEMBL3306990)
Affinity DataKi:  6nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataKi:  8.90nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataKi:  9.60nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50323317(CHEMBL4175848)
Affinity DataKi:  10nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataKi:  10nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataKi:  15nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM38549(MLS000028605 | cid_25096 | CHEMBL170358 | SMR00005...)
Affinity DataKi:  23nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50575522(CHEMBL4878979)
Affinity DataKi:  28nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259839(CHEMBL4100677)
Affinity DataKi:  51nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50614743(CID 27456 | CHEMBL1708510)
Affinity DataKi:  236nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50575553(PYRROLOQUINOLINE QUINONE | CHEBI:18315)
Affinity DataKi:  332nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50259843(CHEMBL4081238)
Affinity DataKi:  352nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50612246(ZAPRINAST | Zaprinast | M&B 22948 | NSC-757885)
Affinity DataKi:  612nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetG-protein coupled receptor 35(Human)
Dalian Institute of Chemical Physics

Curated by ChEMBL
LigandPNGBDBM50440033(Crolom | Cromoglicic Acid | CROMOLYN)
Affinity DataKi:  2.97E+3nMAssay Description:Competitive binding affinity to Nluc-fused human GPR35 expressed in CHO-K1 cells assessed as inhibition constant using furimazine as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed