Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50018951
TargetCyclin-dependent kinase 6(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614148(CHEMBL5277376)
Affinity DataIC50: 13nMAssay Description:Covalent inhibition of CDK6 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614149(CHEMBL4860767)
Affinity DataIC50: 15nMAssay Description:Covalent inhibition of CDK6 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614148(CHEMBL5277376)
Affinity DataIC50: 18nMAssay Description:Covalent inhibition of CDK4 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614150(CHEMBL5277470)
Affinity DataIC50: 19nMAssay Description:Covalent inhibition of CDK6 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614149(CHEMBL4860767)
Affinity DataIC50: 23nMAssay Description:Covalent inhibition of CDK4 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614150(CHEMBL5277470)
Affinity DataIC50: 25nMAssay Description:Covalent inhibition of CDK4 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 4(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 26nMAssay Description:Covalent inhibition of CDK4 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 6(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 38nMAssay Description:Covalent inhibition of CDK6 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 12(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614149(CHEMBL4860767)
Affinity DataIC50: 890nMAssay Description:Covalent inhibition of CDK12 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614148(CHEMBL5277376)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK9 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614149(CHEMBL4860767)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK9 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614150(CHEMBL5277470)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK9 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK9 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614148(CHEMBL5277376)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK12 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50614150(CHEMBL5277470)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK12 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCyclin-dependent kinase 12(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM6309(8-cyclopentyl-6-acetyl-5-methyl-2-{[5-(piperazin-1...)
Affinity DataIC50: 1.00E+3nMAssay Description:Covalent inhibition of CDK12 (unknown origin) using histone H1 as substrate incubated for 10 mins in presence of [gamma-32P]ATP by radioactivity base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed