Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for entry = 50019669
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataKd:  43nMAssay Description:Binding affinity to ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetBromodomain-containing protein 4(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50508013(CHEMBL4541479)
Affinity DataKd:  3.60E+3nMAssay Description:Binding affinity to BRD4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50508013(CHEMBL4541479)
Affinity DataIC50: 8nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50363196(CHEMBL1944698)
Affinity DataIC50: 43nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50434072(CHEMBL2381342)
Affinity DataIC50: 59nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50508013(CHEMBL4541479)
Affinity DataIC50: 86nMAssay Description:Inhibition of ERK5 in human HeLa cells assessed as reduction in EGF-induced ERK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50621637(CHEMBL5421663)
Affinity DataIC50: 88nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50337134(US9266890, IV-6 | Scaffold, B46 | CHEMBL1673046 | ...)
Affinity DataIC50: 240nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 7(Human)
Newcastle University Centre for Cancer

Curated by ChEMBL
LigandPNGBDBM50559802(CHEMBL4303171)
Affinity DataIC50: 810nMAssay Description:Inhibition of ERK5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed