Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50019010
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614612(CHEMBL5280678)
Affinity DataIC50: 20nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50: 30nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614610(CHEMBL5267203)
Affinity DataIC50: 56nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614611(CHEMBL3400936)
Affinity DataIC50: 68nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 6(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614609(CHEMBL5271361)
Affinity DataIC50: 79nMAssay Description:Inhibition of IL-4 induced STAT6 signaling in human HepG2 cells harboring pRL-EF1alpha, pGL3-TK-7xN4 and TOPO-Stat6 plasmid assessed as luciferase ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614612(CHEMBL5280678)
Affinity DataIC50: 90nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetMothers against decapentaplegic homolog 2(Human)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614611(CHEMBL3400936)
Affinity DataIC50: 137nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Johannes Gutenberg-University

Curated by ChEMBL
LigandPNGBDBM50614610(CHEMBL5267203)
Affinity DataIC50: 236nMAssay Description:Inhibition of TGF-beta induced Smad2/3 signaling in human HepG2 cells harboring pRL-EF1alpha, (CAGA)9x-MLP-Luc plasmid assessed as luciferase activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed