Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50020684
TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataIC50: 6.70nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells incubated for 60 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50632673(CHEMBL5430894)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells incubated for 60 mins by liquid scintillation methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM21130(U69,593 | N-methyl-N-(7-(1-pyrrolidinyl)-1-oxaspir...)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells assessed as inhibition constant incubated for 60 mins by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed
TargetKappa-type opioid receptor(Human)
Gwangju Institute of Science and Technology (GIST)

Curated by ChEMBL
LigandPNGBDBM50632673(CHEMBL5430894)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]diprenorphine from human KOR expressed in HEK293 cells assessed as inhibition constant incubated for 60 mins by liquid scintillat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMed