Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50019858
TargetReplicase polyprotein 1ab(2019-nCoV)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50590424(CHEMBL5191209)
Affinity DataIC50: 440nMAssay Description:Inhibition of SARS-CoV-2 PLproMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50590409(CHEMBL5174607)
Affinity DataIC50: 620nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 strain (1564 to 1876 residues) expressed in Escherichia coli BL21(DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50590417(CHEMBL5173886)
Affinity DataIC50: 670nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 strain (1564 to 1876 residues) expressed in Escherichia coli BL21(DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM31524(Naphthalene and Benzamide Derivative, 25 | 5-amino...)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of C-terminal His-tagged SARS-CoV-2 PLpro BetaCoV/Wuhan/WIV04/2019 strain (1564 to 1876 residues) expressed in Escherichia coli BL21(DE3) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Alexandria University

Curated by ChEMBL
LigandPNGBDBM50623833(CHEMBL5438334)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of SARS-CoV-2 PLpro using Arg-Leu-Arg-Gly-Gly-AMC as substrate preincubated for 5 mins followed by substrate addition measured after 6 min...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed