Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50019001
TargetTyrosine-protein kinase Blk(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of BLK (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BMX (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of BTK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of BMX (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of BLK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of BTK (unknown origin) using Blk/Lyntide as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of ITK (unknown origin) using Blk/Lyntide as substrate preincubated for 1 hr followed by substrate addition and measured after 2 hrs in pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetCytoplasmic tyrosine-protein kinase BMX(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 5.70nMAssay Description:Inhibition of BMX (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 13nMAssay Description:Inhibition of BTK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase HCK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 29nMAssay Description:Inhibition of HCK (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase HCK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 30nMAssay Description:Inhibition of HCK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 33nMAssay Description:Inhibition of JAK3 (unknown origin) incubated for 1 hr in presence of ATP by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 34nMAssay Description:Inhibition of SRC (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase Blk(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 36nMAssay Description:Inhibition of BLK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50357312(IBRUTINIB | US9181263, 1 | US9108973, Ref 1 | US92...)
Affinity DataIC50: 44nMAssay Description:Covalent inhibition of NanoLuc fused BTK (unknown origin) expressed in HEK293 cells incubated for 90 mins by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 109nMAssay Description:Covalent inhibition of NanoLuc fused BTK (unknown origin) expressed in HEK293 cells incubated for 90 mins by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 197nMAssay Description:Inhibition of EGFR (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 314nMAssay Description:Covalent inhibition of NanoLuc fused BTK (unknown origin) expressed in HEK293 cells incubated for 90 mins by NanoBRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 344nMAssay Description:Inhibition of ITK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614535(CHEMBL5271284)
Affinity DataIC50: 874nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of SRC (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase HCK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of HCK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ITK (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
San Diego State University

Curated by ChEMBL
LigandPNGBDBM50614536(CHEMBL5278149)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK3 (unknown origin) by Z'LYTE assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/22/2024
Entry Details
PubMed